منابع مشابه
The future of 13C-breath tests.
13C-breath tests are widely applied as a tool to investigate metabolic processes and infectious diseases, but most of them have not yet entered into clinical practice. In order to promote the introduction of more 13C-breath tests into clinical routine application we evaluated the tests so far known with respect to some reasonable criteria, which are valued by one of three marks. The sum sigma o...
متن کامل13C-breath tests for clinical investigation of liver mitochondrial function.
BACKGROUND Mitochondria play a major role in cell energetic metabolism; therefore, mitochondrial dysfunction inevitably participates in or even determines the onset and progression of chronic liver diseases. The assessment of mitochondrial function in vivo, by providing more insight into the pathogenesis of liver diseases, would be a helpful tool to study specific hepatic functions and to devel...
متن کامل13C-breath tests in hepatology (cytosolic liver function).
13C-phenylalanine (PheBT) and 13C-galactose breath tests (GBT) explore non invasively the hepatic functional mass by measuring two enzymatic activities localized into the cytosol of liver cells: the phenylalanine hydroxylase (which converts phenylalanine into tyrosine) and the galactose kinase (which catalyzes the ATP-dependent phosphorylation of galactose to galactose 1-phosphate). Both BTs ar...
متن کامل13C-breath tests in the study of mitochondrial liver function.
Breath tests for "dynamic" liver function evaluation have been proposed several years ago. A variety of carbon-labelled breath tests for the assessment of mitochondrial, microsomal and cytosolic liver function have been described with the aim to increase data on liver disease staging, prognosis, and response to therapy. In the last years a great interest is developed about the use of breath tes...
متن کامل13C-methionine breath tests for mitochondrial liver function assessment.
13C-methionine breath test has been proposed as a non-invasive tool for the assessment of human hepatic mithocondrial function. Two methionine breath labeled with 13C in differents point of his molecular structure have been used for breath test analisys. Aim of this study was to compare two differently 13C-labeled methionines in the evaluation of mitochondrial oxidation in basal conditions and ...
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ژورنال
عنوان ژورنال: Gut
سال: 1998
ISSN: 0017-5749
DOI: 10.1136/gut.43.2008.s23